BDBM50156701 1-(4-bromobenzyl)-4-(4-but-2-ynyxoybenzenesulfonyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL222854

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO

InChI Key InChIKey=MNQFMKHWJNOSIX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156701   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156701(1-(4-bromobenzyl)-4-(4-but-2-ynyxoybenzenesulfonyl...)
Affinity DataIC50: 385nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50156701(1-(4-bromobenzyl)-4-(4-but-2-ynyxoybenzenesulfonyl...)
Affinity DataIC50: 65nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156701(1-(4-bromobenzyl)-4-(4-but-2-ynyxoybenzenesulfonyl...)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156701(1-(4-bromobenzyl)-4-(4-but-2-ynyxoybenzenesulfonyl...)
Affinity DataIC50: 155nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed