BDBM50156714 1-(4-bromobenzyl)-4-(4-prop-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylicAcid hydroxyamide::CHEMBL221717

SMILES ONC(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)S(=O)(=O)c1ccc(OCC#C)cc1

InChI Key InChIKey=SEFCVQRMTNTWJO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156714   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156714(1-(4-bromobenzyl)-4-(4-prop-2-ynyloxybenzenesulfon...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156714(1-(4-bromobenzyl)-4-(4-prop-2-ynyloxybenzenesulfon...)
Affinity DataIC50: 143nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156714(1-(4-bromobenzyl)-4-(4-prop-2-ynyloxybenzenesulfon...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50156714(1-(4-bromobenzyl)-4-(4-prop-2-ynyloxybenzenesulfon...)
Affinity DataIC50: 98nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed