BDBM50156718 1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL222934

SMILES CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO

InChI Key InChIKey=YJZSNVXLDDRADS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156718   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50: 72nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed