BDBM50156722 4-(4-but-2-ynyloxybenzenesulfonyl)-1-(4-methoxybenzyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL222714

SMILES COc1ccc(CN2CCC(CC2)(C(=O)NO)S(=O)(=O)c2ccc(OCC#CC)cc2)cc1

InChI Key InChIKey=QFAMXNMLWJDJPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156722   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156722(4-(4-but-2-ynyloxybenzenesulfonyl)-1-(4-methoxyben...)
Affinity DataIC50: 164nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50156722(4-(4-but-2-ynyloxybenzenesulfonyl)-1-(4-methoxyben...)
Affinity DataIC50: 82nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156722(4-(4-but-2-ynyloxybenzenesulfonyl)-1-(4-methoxyben...)
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156722(4-(4-but-2-ynyloxybenzenesulfonyl)-1-(4-methoxyben...)
Affinity DataIC50: 40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed