BDBM50156725 1-benzyl-4-(4-but-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL385312

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccccc2)CC1)C(=O)NO

InChI Key InChIKey=KRJQQXQOPZJOSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156725   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156725(1-benzyl-4-(4-but-2-ynyloxybenzenesulfonyl)piperdi...)
Affinity DataIC50: 148nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156725(1-benzyl-4-(4-but-2-ynyloxybenzenesulfonyl)piperdi...)
Affinity DataIC50: 47nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156725(1-benzyl-4-(4-but-2-ynyloxybenzenesulfonyl)piperdi...)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50156725(1-benzyl-4-(4-but-2-ynyloxybenzenesulfonyl)piperdi...)
Affinity DataIC50: 90nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed