BDBM50156880 3-{4-[1-(5-Chloro-thiophen-2-ylmethyl)-1H-indol-3-yl]-piperidin-1-ylmethyl}-benzoic acid::3-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-indol-3-yl]-piperidin-1-ylmethyl}benzoic acid::CHEMBL185489

SMILES OC(=O)c1cccc(CN2CCC(CC2)c2cn(Cc3ccc(Cl)s3)c3ccccc23)c1

InChI Key InChIKey=KOKZGSUQOORKGT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156880   

TargetHistamine H1 receptor(Guinea pig)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50156880(3-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-indol-3-y...)
Affinity DataIC50: 330nMAssay Description:Inhibitory concentration against histamine-H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50156880(3-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-indol-3-y...)
Affinity DataIC50: 103nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50156880(3-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-indol-3-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]ketanserin from histamine H2 receptor in human cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed