BDBM50157238 6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-2-(4-methyl-piperazin-1-yl)-nicotinonitrile::CHEMBL359959

SMILES CN1CCN(CC1)c1nc(COC(c2cncn2C)c2ccc(C#N)c(c2)-c2ccccc2C(F)(F)F)ccc1C#N

InChI Key InChIKey=IGAKJJAQQCFWMA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157238   

LigandPNGBDBM50157238(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Bovine geranylgeranyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157238(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157238(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  53nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed