BDBM50157323 CHEMBL3787262

SMILES COc1cc2CC\C(=N/NC(C)=O)C(C)(C)c2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=VSDUCKLXBOURDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157323   

TargetALK tyrosine kinase receptor(Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50157323(CHEMBL3787262)
Affinity DataIC50: 52nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50157323(CHEMBL3787262)
Affinity DataIC50: 201nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed