BDBM50157580 (R)-methyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(tert-butoxycarbonyl)-2-hydroxy-4-phenylbutyl)ureido)-4-methylpentanamido)-4-methylpentanoate::CHEMBL105130

SMILES COC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)N(C[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1

InChI Key InChIKey=WRXCRVWEQSXNRB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157580   

LigandPNGBDBM50157580((R)-methyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(tert-b...)
Affinity DataIC50: 200nMAssay Description:Inhibition of gamma secretase isolated from HeLa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50157580((R)-methyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(tert-b...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50157580((R)-methyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(tert-b...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50157580((R)-methyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(tert-b...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed