BDBM50157633 CHEMBL3779949

SMILES CC1CN(CCC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N

InChI Key InChIKey=QGQKKJOSTCJRNL-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50157633   

TargetCoagulation factor X(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50157633(CHEMBL3779949)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50157633(CHEMBL3779949)
Affinity DataKi:  510nMAssay Description:Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50157633(CHEMBL3779949)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50157633(CHEMBL3779949)
Affinity DataKi:  2.12E+3nMAssay Description:Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50157633(CHEMBL3779949)
Affinity DataKi:  2.77E+3nMAssay Description:Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50157633(CHEMBL3779949)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant thrombin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed