BDBM50157639 CHEMBL3786413

SMILES Nc1ccc2NC(=O)\C(=C/c3cn(CC(O)Cn4cc(\C=C5/C(=O)Nc6ccc(N)cc56)c5ccccc45)c4ccccc34)c2c1

InChI Key InChIKey=HTWOPPGMQLSIKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157639   

TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50157639(CHEMBL3786413)
Affinity DataIC50: 300nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed