BDBM50157878 CHEMBL3786567

SMILES CC1(C)CC[C@@H](COc2cccc(c2)-c2cn([C@@H]3C[C@H](CN4CCC4)C3)c3ncnc(N)c23)O1

InChI Key InChIKey=BCTIPSBBPQBXAG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50157878   

TargetTyrosine-protein kinase Lck(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Her1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3K-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 9nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 100nMAssay Description:Inhibition of Ins receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 690nMAssay Description:Inhibition of EphB4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 970nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Jak1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed