BDBM50158161 CHEMBL3781405

SMILES NC(=N)c1cccc(c1)N1CC(CNC(=O)c2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O

InChI Key InChIKey=UZPVFQUJTASIAP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50158161   

TargetTrypsin(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158161(CHEMBL3781405)
Affinity DataKi:  330nMAssay Description:Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158161(CHEMBL3781405)
Affinity DataKi:  470nMAssay Description:Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158161(CHEMBL3781405)
Affinity DataKi:  750nMAssay Description:Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158161(CHEMBL3781405)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158161(CHEMBL3781405)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158161(CHEMBL3781405)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant thrombin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed