BDBM50158866 CHEMBL3785355

SMILES Clc1cccc(CNC(=O)[C@H](CCCCN[C@@H]2C[C@H]2c2ccccc2)NC(=O)c2ccc(cc2)-c2ccccc2)c1

InChI Key InChIKey=KYDFMNLSOYZOTR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50158866   

TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50158866(CHEMBL3785355)
Affinity DataIC50: 132nMAssay Description:Inhibition of recombinant human LSD1 using H3K4me2 peptide as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50158866(CHEMBL3785355)
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant N-terminal His-tagged KDM1A (1 to 851 residues) (unknown origin) expressed in Escherichia coli using H3K4me2 as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50158866(CHEMBL3785355)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158866(CHEMBL3785355)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAO-B (unknown origin) using MAO substrate incubated for 1 hr by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158866(CHEMBL3785355)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50158866(CHEMBL3785355)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAO-A (unknown origin) using MAO substrate incubated for 1 hr by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2017
Entry Details Article
PubMed