BDBM50159143 CHEMBL3786350

SMILES COC1CN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccc(OC)cc3)cc2)C1

InChI Key InChIKey=JHHMLOGRXQPDON-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159143   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50159143(CHEMBL3786350)Copy SMILESCopy InChI

Affinity DataIC50: 19nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2017
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50159143(CHEMBL3786350)Copy SMILESCopy InChI

Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL