BDBM50159341 CHEMBL3786346

SMILES O=C(N1CC(C1)Oc1ccc(CN2CC3(C2)CCCO3)cc1)c1nnc(o1)-c1ccccc1

InChI Key InChIKey=AGTGRRLYPSCMPU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159341   

TargetMelanin-concentrating hormone receptor 1(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159341(CHEMBL3786346)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159341(CHEMBL3786346)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
LigandPNGBDBM50159341(CHEMBL3786346)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed