BDBM50160066 CHEMBL3787634

SMILES CC(=O)Nc1nc(C)c(s1)-c1ccc(Br)c(c1)S(=O)(=O)NCCO

InChI Key InChIKey=RYCGEXLWAPGHHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160066   

LigandPNGBDBM50160066(CHEMBL3787634)
Affinity DataIC50: 21nMAssay Description:Inhibition of histidine-tagged recombinant human full length PI3Kgamma expressed in insect cells preincubated for 15 mins followed by addition of col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50160066(CHEMBL3787634)
Affinity DataIC50: 33nMAssay Description:Inhibition of histidine-tagged recombinant human full length PI3Kdelta expressed in baculovirus preincubated for 15 mins followed by addition of cold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50160066(CHEMBL3787634)
Affinity DataIC50: 146nMAssay Description:Inhibition of GST-tagged recombinant human full length VPS34 expressed in baculovirus preincubated for 15 mins followed by addition of cold ATP/gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2017
Entry Details Article
PubMed