BDBM50160277 CHEMBL3785536

SMILES COc1ccc(cc1)[C@@H]1[C@H](C(=O)N1C1CCN(CC1)C(=O)n1cncn1)c1ccc(OC)cc1

InChI Key InChIKey=IMVFDAJMJNKUIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160277   

TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160277(CHEMBL3785536)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160277(CHEMBL3785536)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of FAAH in rat brain membranes using using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as reduction in [14C]ethanolamine produ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed