BDBM50160525 CHEMBL3785636

SMILES [H][C@]12C[C@]([H])([C@@H](C)[C@@H](C1)Nc1nc(C)nc3c4ccccn4nc13)C2(C)C

InChI Key InChIKey=KWDFKJNACDSBID-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50160525   

TargetMetabotropic glutamate receptor 1(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160525(CHEMBL3785636)
Affinity DataIC50: 759nMAssay Description:Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160525(CHEMBL3785636)
Affinity DataIC50: 759nMAssay Description:Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160525(CHEMBL3785636)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160525(CHEMBL3785636)
Affinity DataIC50: 3.16E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed