BDBM50160712 CHEMBL3785768

SMILES CC(C)(CN1C(C(=O)NCCCF)c2ccccc2C1=O)c1ccc(Cl)cc1

InChI Key InChIKey=PLURIBOHSAYLHF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50160712   

LigandPNGBDBM50160712(CHEMBL3785768)
Affinity DataIC50: 700nMAssay Description:Inhibition of human Kv1.5 channel by QPatch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
LigandPNGBDBM50160712(CHEMBL3785768)
Affinity DataIC50: 700nMAssay Description:Inhibition of human Kv1.5 channel by QPatch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
LigandPNGBDBM50160712(CHEMBL3785768)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Kv1.5 channel by QPatch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
LigandPNGBDBM50160712(CHEMBL3785768)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50160712(CHEMBL3785768)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed