BDBM50160730 3-{(S)-Methyl-[5-(4-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid [(R)-1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-amide

SMILES CN([C@@H]1CCN(C1)C1CCC(C)(C)CC1)C(=O)N1CCC(C1)N(C)C(=O)c1ccc(s1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HCNXPYMDAMAEAE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160730   

TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160730(3-{(S)-Methyl-[5-(4-trifluoromethyl-phenyl)-thioph...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160730(3-{(S)-Methyl-[5-(4-trifluoromethyl-phenyl)-thioph...)
Affinity DataKi:  338nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed