BDBM50160878 CHEMBL3792712

SMILES COC(=O)c1cccc(NC(=O)c2cc(ccc2O)-n2cc(CCNc3ncnc4ccsc34)nn2)c1

InChI Key InChIKey=KTBMJHSSOVCUPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160878   

TargetAurora kinase B(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50160878(CHEMBL3792712)
Affinity DataIC50: 364nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50160878(CHEMBL3792712)
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed