BDBM50160880 CHEMBL3794018

SMILES COC(=O)c1cccc(NC(=O)c2cc(ccc2O)-n2cc(CNc3ncnc4ccsc34)nn2)c1

InChI Key InChIKey=NLSGVTSSTDOANM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160880   

TargetAurora kinase A(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50160880(CHEMBL3794018)
Affinity DataIC50: 801nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50160880(CHEMBL3794018)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed