BDBM50160993 CHEMBL3793945

SMILES COC(=O)c1cccc(NC(=O)c2cc(ccc2O)-n2cc(nn2)-c2ccc3nccnc3c2)c1

InChI Key InChIKey=WREGKVBLEGKFQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160993   

TargetAurora kinase A(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50160993(CHEMBL3793945)
Affinity DataIC50: 607nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50160993(CHEMBL3793945)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed