BDBM50160998 CHEMBL3793049

SMILES Fc1ccc(NC(=O)Nc2ccc(cn2)-c2nc3CCSCc3c(n2)N2CCOCC2)cc1Cl

InChI Key InChIKey=UNWSKLFPUCHULH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160998   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50160998(CHEMBL3793049)
Affinity DataIC50: 690nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using phosphatidylinositol as substrate incubated for 60 mins by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50160998(CHEMBL3793049)
Affinity DataIC50: 860nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50160998(CHEMBL3793049)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Met kinase (unknown origin) using FAM-labelled peptide substrate incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed