BDBM50161000 CHEMBL3793276

SMILES FC(F)(F)c1cc(NC(=O)N2CCN(CC2)c2nc3CCSCc3c(n2)N2CCOCC2)ccc1Cl

InChI Key InChIKey=JEAKFJZBGDRMIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161000   

TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50161000(CHEMBL3793276)
Affinity DataIC50: 6.26E+3nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50161000(CHEMBL3793276)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Met kinase (unknown origin) using FAM-labelled peptide substrate incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50161000(CHEMBL3793276)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using phosphatidylinositol as substrate incubated for 60 mins by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2017
Entry Details Article
PubMed