BDBM50161327 CHEMBL362651::{(R)-3-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-3-hydroxycarbamoyl-propyl}-carbamic acid benzyl ester::{(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-hydroxycarbamoyl-butyl}-carbamic acid benzyl ester

SMILES CC(C)ON([C@H](CCNC(=O)OCc1ccccc1)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PKVXJRTWUNPBJP-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50161327   

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of Matrix metalloprotease-2 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of Matrix metalloprotease-14 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Matrix metalloprotease-9 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327({(S)-4-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-4-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed