BDBM50161698 CHEMBL178334::[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone

SMILES CC(C)N1CCN(CC1)c1ccc(cc1)C(=O)c1c(sc2cc(O)ccc12)-c1ccc(O)cc1

InChI Key InChIKey=LQEOPHGPHCWOAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161698   

TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161698([6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3...)
Affinity DataIC50: 33.9nMAssay Description:Inhibition of estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161698([6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161698([6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3...)
Affinity DataIC50: 0.280nMAssay Description:Displacement of [3H]-17beta-estradiol from ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161698([6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3...)
Affinity DataIC50: 33.9nMAssay Description:Displacement of [3H]-17beta-estradiol from ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed