BDBM50161712 (4-Chloro-phenyl)-(4-{4-[6-hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenyl}-piperazin-1-yl)-methanone::CHEMBL180707

SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=QYZVZGPAIPNEDN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161712   

TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161712((4-Chloro-phenyl)-(4-{4-[6-hydroxy-2-(4-hydroxy-ph...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161712((4-Chloro-phenyl)-(4-{4-[6-hydroxy-2-(4-hydroxy-ph...)
Affinity DataIC50: 4.02nMAssay Description:Inhibition of estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161712((4-Chloro-phenyl)-(4-{4-[6-hydroxy-2-(4-hydroxy-ph...)
Affinity DataIC50: 9.07nMAssay Description:Displacement of [3H]-17beta-estradiol from ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50161712((4-Chloro-phenyl)-(4-{4-[6-hydroxy-2-(4-hydroxy-ph...)
Affinity DataIC50: 0.220nMAssay Description:Displacement of [3H]-17beta-estradiol from ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed