BDBM50162093 2-(3-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamoylmethyl-1H-indole-6-carboxylic acid::CHEMBL362834

SMILES CN(C)C(=O)Cn1c(c(C2CCCCC2)c2ccc(cc12)C(O)=O)-c1cccc(Cl)c1

InChI Key InChIKey=GKBQYTHQJDXOBC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162093   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162093(2-(3-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataEC50:  4.5nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162093(2-(3-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed