BDBM50162100 3-Cyclohexyl-1-(2-morpholin-4-yl-ethyl)-2-phenyl-1H-indole-6-carboxylic acid::CHEMBL368647

SMILES OC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3)n(CCN3CCOCC3)c2c1

InChI Key InChIKey=PIQDYVXRDTXYLX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162100   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162100(3-Cyclohexyl-1-(2-morpholin-4-yl-ethyl)-2-phenyl-1...)
Affinity DataEC50:  4.60nMAssay Description:Effective concentration for inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virus; n=1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162100(3-Cyclohexyl-1-(2-morpholin-4-yl-ethyl)-2-phenyl-1...)
Affinity DataIC50: 111nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed