BDBM50162148 1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-phenyl]-urea::CHEMBL360526

SMILES COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)cc3)c2cc1OC

InChI Key InChIKey=WEDWUMJCHQDOEH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162148   

TargetVascular endothelial growth factor receptor 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162148(1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162148(1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCdk-related protein kinase 6(Plasmodium falciparum)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50162148(1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...)
Affinity DataIC50: 18nMAssay Description:Inhibition of plasmodium falciparum PK6 incubated for 2 hrs by luciferin-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed