BDBM50162487 3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-4-methyl-tetrahydro-furan-2-carboxylic acid methylamide::CHEMBL194031

SMILES CNC(=O)[C@H]1O[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc23)[C@](C)(O)[C@@H]1O

InChI Key InChIKey=MLUKUGWIZSNCTC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50162487   

TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50162487(3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl...)
Affinity DataKi:  240nMAssay Description:Displacement of [125I]AB-MECA from adenosine A3 receptors in bovine cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50162487(3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl...)
Affinity DataKi:  254nMAssay Description:Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50162487(3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl...)
Affinity DataKi:  320nMAssay Description:Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50162487(3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl...)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]DPCPX binding to adenosine A1 receptors of bovine cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50162487(3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]CGS-21680 binding to adenosine A2A receptors of bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50162487(3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed