BDBM50162648 1,3,7-Triamino-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180884

SMILES NC1=C(C#N)C(=N)CC2Oc3ccc(N)cc3CC12

InChI Key InChIKey=SAAJAIYEZJEWQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162648   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50162648(1,3,7-Triamino-9,9a-dihydro-4aH-xanthene-2-carboni...)
Affinity DataIC50: 530nMAssay Description:Concentration of 50% inhibition by compound towards mitogen activated protein kinase -activated protein kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50162648(1,3,7-Triamino-9,9a-dihydro-4aH-xanthene-2-carboni...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TNFalpha expression in U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed