BDBM50162721 CHEMBL180544::Isoquinoline-3-carboxylic acid ((R)-1-(4-chloro-benzyl)-2-{4-[2-(cyclopropylmethyl-methanesulfonyl-amino)-phenyl]-piperazin-1-yl}-2-oxo-ethyl)-amide

SMILES CS(=O)(=O)N(CC1CC1)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)c1cc2ccccc2cn1

InChI Key InChIKey=URGFKSVRPOAVJF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162721   

TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50162721(Isoquinoline-3-carboxylic acid ((R)-1-(4-chloro-be...)
Affinity DataEC50:  18nMAssay Description:Effective concentration determined against melanocortin-4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50162721(Isoquinoline-3-carboxylic acid ((R)-1-(4-chloro-be...)
Affinity DataIC50: 410nMAssay Description:In vitro inhibitory concentration required against melanocortin 4 receptor using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed