BDBM50162732 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(4-dimethylamino-butyryl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL181110

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)CCCN(C)C

InChI Key InChIKey=OTDAXJIWZBAIMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162732   

LigandPNGBDBM50162732(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(4-dimethyla...)
Affinity DataIC50: 75nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162732(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(4-dimethyla...)
Affinity DataIC50: 395nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed