BDBM50162734 4-(4-But-2-ynyloxy-benzenesulfonyl)-1,1-dioxo-1lambda*6*-[1,4]thiazepane-3-carboxylic acid hydroxyamide::CHEMBL180047

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCS(=O)(=O)CC1C(=O)NO

InChI Key InChIKey=KEEWWGMUNANVLU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162734   

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162734(4-(4-But-2-ynyloxy-benzenesulfonyl)-1,1-dioxo-1lam...)
Affinity DataIC50: 334nMAssay Description:Inhibitory concentration against matrix metalloprotease-1 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50162734(4-(4-But-2-ynyloxy-benzenesulfonyl)-1,1-dioxo-1lam...)
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162734(4-(4-But-2-ynyloxy-benzenesulfonyl)-1,1-dioxo-1lam...)
Affinity DataIC50: 311nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed