BDBM50162735 CHEMBL369574::{2-[4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-[1,4]diazepan-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)CNC(=O)OC(C)(C)C

InChI Key InChIKey=LKFNHCFYLDRUTH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162735   

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162735({2-[4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxyc...)
Affinity DataIC50: 446nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162735({2-[4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxyc...)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibitory concentration against matrix metalloprotease-1 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50162735({2-[4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxyc...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed