BDBM50162736 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-isobutyryl-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isobutyryl-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL361959

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CCC1C(=O)NO)C(=O)C(C)C

InChI Key InChIKey=DOFYUNJDVUXVMB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50162736   

LigandPNGBDBM50162736(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isobutyryl-[...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162736(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isobutyryl-[...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162736(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isobutyryl-[...)
Affinity DataIC50: 142nMAssay Description:Inhibitory concentration against matrix metalloprotease-1 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162736(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isobutyryl-[...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed