BDBM50162744 1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydroxy-4-methanesulfonyl-1,4-diazepane-2-carboxamide::CHEMBL181317

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)S(C)(=O)=O

InChI Key InChIKey=RXYVRCSDLULANF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162744   

LigandPNGBDBM50162744(1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydrox...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162744(1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydrox...)
Affinity DataIC50: 128nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed