BDBM50162745 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-(2-methoxyacetyl)-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(2-methoxy-acetyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL178929

SMILES COCC(=O)N1CCC(N(CC1)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO

InChI Key InChIKey=VAMKUUUJVOOTKN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50162745   

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162745(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-(2...)
Affinity DataIC50: 31nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50162745(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-(2...)
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162745(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-(2...)
Affinity DataIC50: 277nMAssay Description:Inhibitory concentration against matrix metalloprotease-1 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162745(4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-(2...)
Affinity DataIC50: 31nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed