BDBM50162751 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(propane-1-sulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL181365

SMILES CCCS(=O)(=O)N1CCCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1

InChI Key InChIKey=LVVFBDASYOIWFN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162751   

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162751(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(propane-1-s...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibitory concentration against matrix metalloprotease-1 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162751(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(propane-1-s...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50162751(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(propane-1-s...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed