BDBM50162755 (S)-3-(6-Methoxy-pyridin-3-yl)-7-oxo-9-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-nonanoic acid::CHEMBL181366

SMILES COc1ccc(cn1)[C@@H](CCCC(=O)CCc1ccc2CCCNc2n1)CC(O)=O

InChI Key InChIKey=YJTFZPUDXPSWOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162755   

TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162755((S)-3-(6-Methoxy-pyridin-3-yl)-7-oxo-9-(5,6,7,8-te...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of 2(S)-(4-125I-benzenesulphonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162755((S)-3-(6-Methoxy-pyridin-3-yl)-7-oxo-9-(5,6,7,8-te...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of alphaIIb-beta3 integrin mediated platelet aggregation (PLAGGIN15)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed