BDBM50162773 3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid::CHEMBL360771

SMILES CC(C(c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N(C)C

InChI Key InChIKey=YLMRCYCGLCIPMC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50162773   

TargetCytochrome P450 26A1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 20nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 20nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CYP26A1 in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Selectivity towards cytochrome P450 1A2 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Selectivity towards cytochrome P450 2D6 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Selectivity towards cytochrome P450 2C9 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 6.30E+3nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162773(3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl...)
Affinity DataIC50: 6.30E+3nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed