BDBM50162894 CHEMBL361972::[2-(4-Fluoro-benzenesulfonylamino)-6,7,8,9,10,10a-hexahydro-5aH-cyclohepta[b]indol-5-yl]-acetic acid

SMILES OC(=O)CN1C2CCCCCC2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12

InChI Key InChIKey=HNROBLLXPPBPNO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162894   

TargetProstaglandin D2 receptor 2(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50162894([2-(4-Fluoro-benzenesulfonylamino)-6,7,8,9,10,10a-...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calciumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50162894([2-(4-Fluoro-benzenesulfonylamino)-6,7,8,9,10,10a-...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calciumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50162894([2-(4-Fluoro-benzenesulfonylamino)-6,7,8,9,10,10a-...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibitory activity for binding of PGD-2 in hTP binding assay using HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed