BDBM50163069 1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL361213

SMILES CN1CCC[C@@H]1Cc1cn(c2ccc(Cl)cc12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=UKKAXWAHUHWUQF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50163069   

Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50163069(1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrroli...)
Affinity DataKi:  1.40nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50163069(1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrroli...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50163069(1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrroli...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed