BDBM50163166 7-Phenyl-1-(5-thiophen-2-yl-oxazol-2-yl)-heptan-1-one::7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-one::CHEMBL178071

SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1cccs1

InChI Key InChIKey=CFBRVIBLBRUALR-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50163166   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163166(7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163166(7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163166(7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163166(7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-...)
Affinity DataKi:  55nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50163166(7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-...)
Affinity DataKi:  55nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163166(7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-...)
Affinity DataKi:  55nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50163166(7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-...)
Affinity DataKi:  55nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed