BDBM50163220 3-Methyl-3'',4'',5'',6''-tetrahydro-2''H-[2,4'']bipyridinyl-1''-carboxylic acid (4-trifluoromethyl-phenyl)-amide::CHEMBL175383

SMILES Cc1cccnc1C1CCN(CC1)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=DOUBDNJQWXEMSU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50163220   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163220(3-Methyl-3'',4'',5'',6''-tetrahydro-2''H-[2,4'']bi...)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of human transient receptor potential vanilloid 1 receptor (n=4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163220(3-Methyl-3'',4'',5'',6''-tetrahydro-2''H-[2,4'']bi...)
Affinity DataIC50: 390nMAssay Description:Inhibition of rat transient receptor potential vanilloid 1 receptor (n=4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163220(3-Methyl-3'',4'',5'',6''-tetrahydro-2''H-[2,4'']bi...)
Affinity DataEC50:  1.96E+3nMAssay Description:Effective concentration against rat transient receptor potential vanilloid 1 receptor (n=2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed