BDBM50163314 CHEMBL3793083

SMILES CCC(CC)N(Cc1ccc(cc1)C(O)=O)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=YAGYWQLXJIWAKJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50163314   

TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50: 120nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 40 production by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50: 120nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 40) production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50: 130nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50: 130nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 42) production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed