BDBM50163320 CHEMBL3792858

SMILES COC(=O)c1ccc(CN(c2cc(F)ccc2F)S(=O)(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=NIAFKLUKSJLVNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163320   

TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163320(CHEMBL3792858)
Affinity DataIC50: 580nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 40 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed